Roxithromycin Impurity R - Names and Identifiers
Roxithromycin Impurity R - Physico-chemical Properties
Molecular Formula | C40H74N2O15
|
Molar Mass | 823.02 |
Melting Point | 96-98°C |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | -20°C Freezer |
Roxithromycin Impurity R - Introduction
N-Demethyl Roxithromycin is a derivative of Roxithromycin with a molecular formula of C42H69N1O15 and a relative molecular mass of 825.0g/mol. It is a white crystalline powder, insoluble in water and slightly soluble in ethanol and ether.
N-Demethyl Roxithromycin is widely used in the field of medicine. As a broad-spectrum antibiotic, it can treat a variety of bacterial infections. It has strong antibacterial activity and has good curative effect on respiratory tract, urogenital system, skin and soft tissue infection.
The method for preparing N-Demethyl Roxithromycin can be obtained by demethylation reaction of Roxithromycin. The specific step is that Roxithromycin is reacted with dimethyl phthalate, and a base is further added to obtain Roxithromycin N-Demethyl.
For safety information, N-Demethyl Roxithromycin should avoid contact with strong oxidizing agents. During storage and use, keep away from fire and heat sources and keep good ventilation. Wear appropriate personal protective equipment during handling and avoid direct contact with skin and eyes. If the contact causes discomfort, rinse immediately with water and seek medical help. Read the relevant chemical safety technical instructions carefully before use and follow the correct operating procedures.
Last Update:2024-04-09 20:02:46